![]() Targeted genome editing of sweet orange using Cas9/sgRNA. Hendel A, Kildebeck EJ, Fine EJ, Clark JT, Punjya N, Sebastiano V, Bao G, Porteus MH.Ĭell Rep. Quantifying genome-editing outcomes at endogenous loci with SMRT sequencing. Pusapati GV, Hughes CE, Dorn KV, Zhang D, Sugianto P, Aravind L, Rohatgi R.ĭev Cell. Epub 2014 Feb 3.ĮFCAB7 and IQCE regulate hedgehog signaling by tethering the EVC-EVC2 complex to the base of primary cilia. Gostissa M, Schwer B, Chang A, Dong J, Meyers RM, Marecki GT, Choi VW, Chiarle R, Zarrin AA, Alt FW. IgH class switching exploits a general property of two DNA breaks to be joined in cis over long chromosomal distances. Epub 2013 Dec 26.Ī synthetic lethal screen identifies FAT1 as an antagonist of caspase-8 in extrinsic apoptosis.ĮMBO J. Mashiko D, Young SA, Muto M, Kato H, Nozawa K, Ogawa M, Noda T, Kim YJ, Satouh Y, Fujihara Y, Ikawa M.ĭev Growth Differ. doi: 10.1242/bio.20137120.įeasibility for a large scale mouse mutagenesis by injecting CRISPR/Cas plasmid into zygotes. Mutagenesis and homologous recombination in Drosophila cell lines using CRISPR/Cas9.īassett AR, Tibbit C, Ponting CP, Liu JL.īiol Open. Mashiko D, Fujihara Y, Satouh Y, Miyata H, Isotani A, Ikawa M. Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA. Epub 2013 Aug 11.ĬRISPR/Cas-induced double-strand breaks boost the frequency of gene replacements for humanizing the mouse Cnr2 gene.īiochem Biophys Res Commun. Epub 2013 Jun 6.ĬRISPR/Cas9 systems targeting beta-globin and CCR5 genes have substantial off-target activity. Shen T, Yang WS, Yi YS, Sung GH, Rhee MH, Poo H, Kim MY, Kim KW, Kim JH, Cho JY.Įvid Based Complement Alternat Med. Articles Citing pX330-U6-Chimeric_BB-CBh-hSpCas9 ArticlesĪP-1/IRF-3 Targeted Anti-Inflammatory Activity of Andrographolide Isolated from Andrographis paniculata.
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